INNOVABIOVASC
- CATANZARO 4.0
- MATE
- A device and a method for installing a plug in a wall
- Innovation Pole of Health Technologies 2018-2023
- NADITEMM
- I PRAY
- Merck project
- Creating a Safe Home Environment
- Tech4You
- GENADIS-D
- OEDIPUS
- WEEPIE
- INNOVABIOVASC
- Biomind
- Hearthdrive – Advanced services for more effective and efficient integrated clinical management of heart failure and its main comorbidities
- ABRAM – Advanced biosafety in tissues regeneration and in biomedicine
- ALIFUD – Development of new functional foods effective for women's health in post-menopausal osteoporosis
- ICaRe – Calabrian Infrastructure for regenerative medicine: generation of bio-banks for the cryopreservation of human stem cells and bone tissue for clinical use and design and development of innovative bioscaffold
- Locubirehab – Low cost ubiquitous rehab assistant
- Neuromeasures – Development of innovative processes and to support the early diagnosis of motor disorders services, behavioral and mnesici in Parkinson's disease and Alzheimer's disease
- Optima Cardiopaths – Innovative tools for optimizing clinical management and endovascular therapy of cardiovascular diseases
INNOVABIOVASC – INNOVAtive strategies for the delivery of autophagy-Based cardIOVASCular therapies
Description:
The INNOVABIOVASC project aims to develop a new therapeutic strategy for cardiovascular diseases, based on the use of nanomedicine and a smart inhaler to stimulate autophagy at the cardiac level.
The approach involves the combined administration of trehalose and the Tat-Beclin D11 peptide, substances capable of promoting the activation of autophagy and potentially improving cardiac function. To overcome the limits of traditional administration, the active ingredients will be conveyed through innovative nanoparticles capable of reaching the heart more effectively.
The system will be integrated into a smart inhaler equipped with sensors and Artificial Intelligence algorithms, capable of synchronizing drug delivery with the patient's respiratory cycle and optimizing the deposition of nanoparticles. The device will also be reusable and sustainable, with refillable or replaceable cartridges made from recyclable materials.
Project partners:
- Biotecnomed S.c.a.r.l.
- Magna Graecia University of Catanzaro
- IRCCS Neuromed (Mediterranean Neurological Institute)
Funds: xxxxx
Total investment: € 5.457.187,50
Total contribution: € 3.775.000,00
Period: xxxx
